Protein name:
Krueppel-like factor 1 ;
Alternative:
Erythroid krueppel-like transcription factor (EKLF) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with CBP and EP300; the interactions enhance the transactivation activity. Interacts with PCAF; the interaction does not acetylate EKLF and inhibits its transactivation activity (By similarity). Interacts with CDH4; the interaction is SUMO-dependent and leads to transcriptional repression.
Function:
Transcription regulator of erythrocyte development. Binds to the CACCC box in the beta-globin gene promoter and activates transcription. Probably serves as a general switch factor for erythroid development. When sumoylated, acts as a transcriptional repressor by promoting interaction with CDH2/MI2beta and also represses megakaryocytic differentiation.
Subcellular Location:
Nucleus
Colocalizes with SUMO1 in nuclear speckles.
Protein Attributes:
50:
MASAETVLPS | ISTLTTLGQF | LDTQEDFLKW | WRSEETQDLG | PGPPNPTGPS |
100:
LHVSLKSEDP | SGEDDERDVT | CAWDPDLFLT | NFPGSESPGT | SRTCALAPSV |
150:
GPVAQFEPPE | SLGAYAGGPG | LVTGPLGSEE | HTSWAHPTPR | PPAPEPFVAP |
200:
ALAPGLAPKA | QPSYSDSRAG | SVGGFFPRAG | LAVPAAPGAP | YGLLSGYPAL |
250:
YPAPQYQGHF | QLFRGLAAPS | AGGTAPPSFL | NCLGPGTVAT | ELGATAIAGD |
300:
AGLSPGTAPP | KRSRRTLAPK | RQAAHTCGHE | GCGKSYSKSS | HLKAHLRTHT |
350:
GEKPYACSWD | GCDWRFARSD | ELTRHYRKHT | GHRPFCCGLC | PRAFSRSDHL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Krueppel-like factor 1
ELISA Kit for Mouse Krueppel-like factor 1
CLIA Kit for Mouse Krueppel-like factor 1
CLIA Kit for Mouse Krueppel-like factor 1
Polyclonal Antibody for Mouse Krueppel-like factor 1
Polyclonal Antibody for Mouse Krueppel-like factor 1
Monoclonal Antibody for Mouse Krueppel-like factor 1
Monoclonal Antibody for Mouse Krueppel-like factor 1
Protein for Mouse Krueppel-like factor 1
Protein for Mouse Krueppel-like factor 1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
129 .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
strain :
129 .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT THR-23;FUNCTION;MUTAGENESIS OF THR-23 AND 25-GLU-ASP-26
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION AT LYS-270 AND LYS-284;FUNCTION;MUTAGENESIS OF LYS-270 AND LYS-284
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH SIN3A AND HDAC1;MUTAGENESIS OF LYS-284; HIS-295; HIS-325 AND HIS-353
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUMOYLATION AT LYS-56;INTERACTION WITH CHD4;FUNCTION;MUTAGENESIS OF LYS-56